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Objective:To investigate the clinical effect of plasma exchange in the treatment of patients with severe hepatitis.Methods:From December 2011 to December 2018, 84 patients with severe hepatitis admitted to the Third People's Hospital of Linfen were selected, and they were divided into control group ( n=41) and observation group ( n=41)according to the random digital table method.The control group was treated with routine treatment, and the observation group was treated with plasma exchange at the same time.The therapeutic effect of the two groups was observed. Results:The total effective rate of the observation group was 73.17%(30/41), which was significantly higher than that of the control group[51.22%(21/41)] (χ 2=4.201, P<0.05). After treatment, the ALB, AST, ALT, TBIL levels in the control group were (36.74±4.25)g/L, (247.85±12.36)U/L, (214.57±10.14)U/L, (288.96±16.30)μmol/L, respectively, which in the observation group were (45.14±5.30)g/L, (162.65±8.30)U/L, (120.74±6.33)U/L, (241.74±15.02)μmol/L, respectively, the differences between the two groups were statistically significant( t=7.917, 36.642, 50.261, 13.641, all P<0.05). After treatment, the interferon gamma(IFN-γ), tumor necrosis factor alpha(TNF-α), interleukin 6(IL-6) levels in the control group were (318.96±92.15)ng/L, (334.74±102.58)ng/L, (65.89±6.33)ng/L, respectively, which in the observation group were (261.15±89.62)ng/L, (274.15±85.12)ng/L, (54.36±5.23)ng/L, respectively, the differences between the two groups were statistically significant( t=2.879, 2.910, 8.991, all P<0.05). There was no statistically significant difference in the incidence of adverse reactions between the two groups ( P>0.05). Conclusion:Plasma exchange in the treatment of severe hepatitis can improve the clinical therapeutic effect, improve its liver function, reduce the level of inflammatory cytokines, and has no adverse reactions.
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The AIDS epidemic in men who have sex wlth men (MSM) in recent years showed a sharp upward trend, looking for behavioral intervention strategies should be imperative. Fear appeals by fear prompted intervention received intervention information, provide a new breakthrough to achieve better effect of propaganda and intervention. After over 70 years development, the Fear Appeal generated from the driver model that proposed the fear decided the effectiveness of behavior intervention, to the extended parallel process model theory which integrated protection motivation theory and parallel process theory, both of which believed the fear is just one of the estimators, suggested fear is the key factor. The fear appeal theory is turning to be even more comprehensive and accurate. As an important theoretical basement, the fear appeal is still developing, and need more work to make it perfection.
Subject(s)
Humans , Male , Acquired Immunodeficiency Syndrome , Psychology , Fear , Health Promotion , Methods , Homosexuality, MaleABSTRACT
Objective:To explore the relationship among lottery buying behaviors,risk attitudes and lottery re-lated cognitive distortions,in order to propose suggestions about the intervention of problem lottery players and the healthy development of the lottery.Methods:Totally 228 lottery players (120 males,108 females;150 unmarried,78 married)sampled from Jinan were asked to fill out the Questionnaire of Lottery Buying Behavior (LBB),Domain Specific Risk-Taking Scale (DOSPERT)and Lottery Related Cognitive Distortions Scale (LRCD).Correlation a-nalysis and path analysis were used to analyze the data.Results:The scores of irrational behavior of LBB were posi-tively correlated with the DOSPERT total scores and its factor scores of recreation and gambling,and positively cor-related with the LRCD total scores and its factor scores except optimistic (r=0.17 -0.34,Ps<0.01 ).While the scores of rational behavior of LBB were negatively correlated with DOSPERT total scores and factor scores of rec-reation and gambling,and negatively correlated with LRCD total scores and its factor scores of illusion of control, illusory correlation,over optimistic and gamblers'fallacy (r=-0.18 --0.37,Ps<0.01 ).Path analysis showed that lottery related cognitive distortions had complete mediating effect between risk attitudes and irrational behaviorsof buying lotteries.Lottery related cognitive distortions partially mediate the relationship between risk attitudes and rational behaviors of buying lotteries.Conclusion:It suggests that the higher risk attitudes the lottery players hold, the greater cognitive distortions they will have,which in turn the irrational behaviors of buying lotteries might easily to have.
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Objective To detect early diagnosis significance of cardiopulmonary exercise test in idiopathic pulmonary fibrosis(IPF).Methods 32 cases of IPF were individed into 2 groups,early-stage group (19cases) and non-early-stage group (13cases).All IPF patients and 22 healthy persons as control were performed cardiopulmonary exercise test.Results All indexes of cardiopulmonary exercise test were significantly different between the early-stage group and the control group,the non-early-stage group and the control group,the non-early-stage group and the early-stage group.Conclusion Cardiopulmonary exercise test markedly raises value early diagnosis in IPF.